Time-course swRNA-seq uncovers a hierarchical gene regulatory network in controlling the response-repair-remodeling after wounding
Abstract Wounding initiates intricate responses crucial for tissue repair and regeneration.Yet, the gene regulatory networks governing wound healing remain poorly understood.Here, employing single-worm RNA sequencing (swRNA-seq) across 12 time-points, we delineated a three-stage wound repair process in C.elegans: response, repair, and remodeling.In